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Polycystic ovary syndrome, or PCOS, is the most common endocrine disorder in women of reproductive age. The syndrome is named after the characteristic cysts which may form on the ovaries, though it is important to note that this is a sign and not the underlying cause of the disorder. A review of the international evidence found that the prevalence of PCOS could be as high as 26% among some populations. Despite its high prevalence, the exact cause of PCOS remains uncertain. The primary characteristics of this syndrome include: hyperandrogenism, anovulation, insulin resistance, and neuroendocrine disruption.